【國醫】病理實驗期末考 ｜大三上

日期：
Disease: Blebs and Emphysematous change
Organ: Lung
  1. Enlargement of the air spaces distal to the terminal bronchiole, accompanied by destruction of their walls.
  2. Pleural fibrosis with chronic inflammation.
  3. Loss of alveolar walls and coalescence of adjacent alveoli.
  4. Bleb formation in the subpleural area.

Disease: Adenocarcinoma
Organ: Lung
  1. Glandular differentiation with tubules or papillae and mucin secretion; bronchioloalveolar (BAC), colloid, hepatoid, signet ring and undifferentiated subtypes
  2. Glandular tumor nests with hyperchromatism, nuclear pleomorphism, prominent nucleoli, infiltrate in the parenchyma
  3. Papillary and hobnail growth patterns are noted. 



 Organ: Lymph node
Disease: Diffuse large B cell lymphoma
  1. Diffusely effacement of the normal architecture of the lymph node
  2. Large size (more than 2X) atypical lymphoid cells infiltration
  3. Nuclear pleomorphism, vesicular chromatin and prominent nucleoli.
細胞可分成兩類,一類較大較透亮(是腫瘤),一類較黑、小(正常 lymphocyte)
癌細胞較透亮，看得到核仁，感覺細胞較淡色、大顆、有明顯核仁，且細胞間會聚集,癌細胞間界線不明顯





 Organ：bone marrow
Diease：Plasma cell myeloma
  1. Hypercellularity of bone marrow
  2. Diffuse atypical plasma cells in large clusters in the bone marrow
  3. Tumor cells make up more than 30% of marrow cells






 Organ: Soft tissue
Disease: Tophi
Crystals surrounded by inflammatory cells including macrophages, lymphocytes, plasma cells and giant cells



 Organ: Soft tissue
Disease: Liposarcoma, well differentiated
  1. Marked variation in adipocyte size.
  2. Presence of atypical, hyperchromatic stromal cells.
  3. Varying number of lipoblasts are present.




 Organ: Colon
Disease: Adenocarcinoma
Composed of tumor cells with hyperchromatic and pleomorphic nuclei arranged in glandular, fusional and cribriform patterns invading to pericolic(peripheral) fat. A lymph node with metastatic adenocarcinoma is also seen.

 Organ：Lung
Disease：Tuberculosis
  1. The clear spaces are surrounded by nodular collections of epithelioid histiocytes.
  2. The areas around the granuloma show chronic inflammation.
  3. Langhans giant cell.
  4. Central necrosis.



 Organ:artery
Disease：Atherosclerosis
描述：
1.There is plaque formation and hyaline deposition in the intima and media.特徵是血管內膜和中膜堆積的斑塊和細胞外基質。
2.Focal fatty change and organized thrombus are also seen.可見變性脂肪和血栓
3.There is calcification.有鈣化
4.See a circle like a donut.看到一圈圈的像是甜甜圈





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